Leflunomide

Leflunomid

Engelsk definition

An isoxazole derivative that inhibits dihydroorotate dehydrogenase, the fourth enzyme in the pyrimidine biosynthetic pathway. It is used an immunosuppressive agent in the treatment of RHEUMATOID ARTHRITIS and PSORIATIC ARTHRITIS.

Svenska synonymer

Arava

Engelska synonymer

N-(4-Trifluoromethyphenyl)-5-methylisoxazole-4-carboxamide HWA 486 HWA-486 HWA486 SU101 Arava