Survivin

Survivin

Engelsk definition

An apoptosis inhibitory protein that contains a single baculoviral IAP repeat (BIR) domain. It associates with MICROTUBULES and functions to regulate cell proliferation as a component of the chromosome passage protein complex (CPC), performing essential roles for localization of the complex, chromosome alignment, segregation during MITOSIS and CYTOKINESIS, and assembly of the MITOTIC SPINDLE. It is expressed by fetal kidney and liver cells and highly expressed in ADENOCARCINOMA and high-grade LYMPHOMA.

Svenska synonymer

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Engelska synonymer

BIRC5 Protein Baculoviral IAP Repeat-containing Protein 5 Baculoviral IAP Repeat containing Protein 5