Inhibitor of Growth Protein 1

Engelsk definition

A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and chromosomal rearrangements of the ING1 gene are associated with different cancers including HEAD AND NECK NEOPLASMS.

Svenska synonymer

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Engelska synonymer

p33ING Protein ING1 Protein ING-1 Protein ING 1 Protein