A DEAD box RNA helicase that contains two N-terminal CASPASE ACTIVATION AND RECRUITMENT DOMAINS. It functions as a sensor of viral NUCLEIC ACIDS such as DOUBLE-STRANDED RNA and activates the INNATE IMMUNE RESPONSE by inducing the expression of INTERFERON-ALPHA and INTERFERON-BETA. It may also regulate cell growth and APOPTOSIS.
Inga svenska synonymer finns.
Helicase, IFIH1 Interferon-Induced — IFIH1 Interferon-Induced Helicase — Interferon Induced Helicase, IFIH1 — Helicard — Interferon Induced with Helicase C Domain 1 — IFIH1 Protein — CADM-140 Autoantigen — Autoantigen, CADM-140 — CADM 140 Autoantigen — Interferon-Induced Helicase C Domain-Containing Protein 1 — Interferon Induced Helicase C Domain Containing Protein 1 — Melanoma Differentiation-Associated Protein 5 — Melanoma Differentiation Associated Protein 5