AlkB Homolog 4, Lysine Demethylase

Engelsk definition

A dioxygenase and alkylation repair homolog that mediates demethylation of ACTIN monomethylated at 'Lys-84' (K84me1). Demethylation of actin LYSINE 84 (K84me1) is required for maintaining actin and MYOSIN dynamics to support normal cleavage furrow ingression during CYTOKINESIS and CELL MIGRATION. It may also be involved in transcription regulation.

Svenska synonymer

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Engelska synonymer

Alpha-Ketoglutarate-Dependent Dioxygenase Alkb Homolog 4 Alpha Ketoglutarate Dependent Dioxygenase Alkb Homolog 4 Alkylated DNA Repair Protein AlkB Homolog 4