En DNA-bindande, anonym kärnreceptor som positivt reglerar uttryck av ARNTL-transkriptionsfaktorer och som medverkar i regleringen av den biologiska klockan. Proteinet spelar också en roll för nervcellers fortlevnad och differentiering på så sätt att funktionsbortfallsmutationer i dess gen hos möss resulterar i en fenotyp kallad "nervösa möss".
A DNA-binding orphan nuclear receptor that positively regulates expression of ARNTL TRANSCRIPTION FACTORS and is a regulatory component of the circadian clock system. The protein also has a role in neuron cell survival and differentiation in that loss of function mutations of its gene result in the mouse phenotype referred to as the STAGGERER MOUSE.
Inga svenska synonymer finns.
Nuclear Receptor NR1F1 — NR1F1, Nuclear Receptor — Receptor NR1F1, Nuclear — Retinoid-Related Orphan Receptor-alpha — Retinoid Related Orphan Receptor alpha — Nuclear Receptor ROR-alpha — Nuclear Receptor ROR alpha — RAR-Related Orphan Receptor A — RAR Related Orphan Receptor A — Retinoid-Related Orphan Receptor-alpha4 — Retinoid Related Orphan Receptor alpha4 — Nuclear Receptor RZR-alpha — Nuclear Receptor RZR alpha — RZR-alpha, Nuclear Receptor — Retinoid-Related Orphan Receptor-alpha3 — Retinoid Related Orphan Receptor alpha3 — Retinoid-Related Orphan Receptor-alpha1 — Retinoid Related Orphan Receptor alpha1 — Retinoid-Related Orphan Receptor-alpha2 — Retinoid Related Orphan Receptor alpha2