Flap Endonucleases

Flap-endonukleaser

Engelsk definition

Endonucleases that remove 5' DNA sequences from a DNA structure called a DNA flap. The DNA flap structure occurs in double-stranded DNA containing a single-stranded break where the 5' portion of the downstream strand is too long and overlaps the 3' end of the upstream strand. Flap endonucleases cleave the downstream strand of the overlap flap structure precisely after the first base-paired nucleotide, creating a ligatable nick.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Endonucleases, Flap Flap Endonuclease Endonuclease, Flap Flap Endonuclease-1 Endonuclease-1, Flap Flap Endonuclease 1 RTH-1 Nuclease Nuclease, RTH-1 RTH 1 Nuclease RAD2 Homolog-1 Nuclease RAD2 Homolog 1 Nuclease FEN-1 Fen1 Protein