1-Alkyl-2-acetylglycerophosphocholine Esterase

1-alkyl-2-acetylglycerofosfokolinesteras

Engelsk definition

A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA.

Svenska synonymer

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Engelska synonymer

1 Alkyl 2 acetylglycerophosphocholine Esterase Esterase, 1-Alkyl-2-acetylglycerophosphocholine PAF Acetylhydrolase II Acetylhydrolase II, PAF Platelet-Activating Factor Hydrolase Factor Hydrolase, Platelet-Activating Hydrolase, Platelet-Activating Factor Platelet Activating Factor Hydrolase PAF 2-Acylhydrolase PAF 2 Acylhydrolase Lipoprotein-Associated Phospholipase A2 Lipoprotein Associated Phospholipase A2 Phospholipase A2, Lipoprotein-Associated Lp-PLA(2) Lp-PLA2 Lp PLA2 PAF 2-Acetylhydrolase 2-Acetylhydrolase, PAF PAF 2 Acetylhydrolase PAF Acetylhydrolase Acetylhydrolase, PAF Lipoprotein-Associated Phospholipase A(2) Platelet-activating Factor Acetylhydrolase IB Platelet activating Factor Acetylhydrolase IB