Specifika hydroximetylglutaryl-CoA-reduktaser som utnyttjar kofaktor NADP. Reaktionen är: (R)-mevalonat + CoA + 2 NADP+ = (S)-3-hydroxi-3-metylglutaryl-CoA + 2 NADPH + 2 H+. Leverenzymer tillhörande denna klass ingår i biosyntesen av kolesterol. EC 1.1.1.34.
Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. In liver enzymes of this class are involved in cholesterol biosynthesis.
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NADP-dependent Hydroxymethylglutaryl-CoA-Reductases — Hydroxymethylglutaryl-Coenzyme A Reductase (NADP) — Hydroxymethylglutaryl-CoA-Reductase (NADP) — 3-Hydroxy-3-methylglutaryl-coenzyme A reductase, NADP-dependent — 3 Hydroxy 3 methylglutaryl coenzyme A reductase, NADP dependent — HMG CoA-Reductases, NADP-Dependent — CoA-Reductases, NADP-Dependent HMG — HMG CoA Reductases, NADP Dependent — NADP-Dependent HMG CoA-Reductases