Specifika hydroximetylglutaryl-CoA-reduktaser som utnyttjar kofaktor NAD. Reaktionen är: (R)-mevalonat + CoA + 2 NAD+ = 3-hydroxi-3-metylglutaryl-CoA + 2 NADH + 2 H+. Denna enzymklass spelar en katabolisk roll i mikroorganismer som t ex Pseudomonas mevalonii, där den oxidativt acetylerar mevalonsyra till att bilda 3-hydroxi-3-metylglutaryl-CoA och NADH. EC 1.1.1.88.
Specific hydroxymethylglutaryl CoA reductases that utilize the cofactor NAD. This class of enzymes performs a catabolic role in microorganisms such as Pseudomonas mevalonii where it oxidatively acetylates MEVALONIC ACID to form 3-HYDROXY-3-METHYLGLUTARYL-COENZYME A and NADH.
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NAD-Dependent Hydroxymethylglutaryl-CoA Reductases — 3-Hydroxy-3-methylglutaryl CoA-Reductase, NAD-Dependent — CoA-Reductase, NAD-Dependent 3-Hydroxy-3-methylglutaryl — NAD-Dependent 3-Hydroxy-3-methylglutaryl CoA-Reductase — Hydroxymethylglutaryl CoA Reductase, NAD-Dependent — Hydroxymethylglutaryl CoA Reductase, NAD Dependent — HMG CoA Reductase, NAD-Dependent — HMG CoA Reductase, NAD Dependent — HMG CoA Reductases, NAD-Dependent — HMG CoA Reductases, NAD Dependent