Frameshift Mutation

Läsramsmutation

Svensk definition

En mutationstyp som uppkommer när ett antal nukleotider ej delbara med tre faller bort eller sätts in i en kodningssekvens, och därmed ändrar läsramen för hela sekvensen nedströms mutationen. Sådana mutationer kan framkallas av vissa mutagener eller uppstå spontant.

Engelsk definition

A type of mutation in which a number of NUCLEOTIDES deleted from or inserted into a protein coding sequence is not divisible by three, thereby causing an alteration in the READING FRAMES of the entire coding sequence downstream of the mutation. These mutations may be induced by certain types of MUTAGENS or may occur spontaneously.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Frameshift Mutations Mutations, Frameshift Out-of-Frame Mutation Mutation, Out-of-Frame Mutations, Out-of-Frame Out of Frame Mutation Out-of-Frame Mutations Frame Shift Mutation Frame Shift Mutations Mutation, Frame Shift Mutations, Frame Shift Mutation, Frameshift Out-of-Frame Insertion Insertion, Out-of-Frame Insertions, Out-of-Frame Out of Frame Insertion Out-of-Frame Insertions Out-of-Frame Deletion Deletion, Out-of-Frame Deletions, Out-of-Frame Out of Frame Deletion Out-of-Frame Deletions