Drug Design

Läkemedelsdesign

Svensk definition

Den molekylära utformningen av läkemedel för specifika ändamål (såsom DNA-bindning, enzymhämning, verkan mot tumörer osv), baserad på kännedom om molekylära egenskaper, som t ex funktionella gruppers aktivitet, molekylgeometri, elektronstruktur och information om analoga molekyler. Läkemedelsdesign bygger på datorstödd molekylär modelleringsteknik och omfattar inte farmakokinetik, dosanalys eller analys av läkemedelsadministrering.

Engelsk definition

The molecular designing of drugs for specific purposes (such as DNA-binding, enzyme inhibition, anti-cancer efficacy, etc.) based on knowledge of molecular properties such as activity of functional groups, molecular geometry, and electronic structure, and also on information cataloged on analogous molecules. Drug design is generally computer-assisted molecular modeling and does not include PHARMACOKINETICS, dosage analysis, or drug administration analysis.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Drug Designs Pharmaceutical Design Design, Pharmaceutical Pharmaceutical Designs Drug Modeling Drug Modelings Computer-Aided Drug Design Computer Aided Drug Design Computer-Aided Drug Designs Drug Design, Computer-Aided Computerized Drug Design Computerized Drug Designs Drug Design, Computerized