2',5'-Oligoadenylate Synthetase

2`5`-oligoadenylatsyntetas

Svensk definition

Ett enzym som katalyserar omvandlingen av ATP till en rad (2´-5´)-bundna oligoadenylater och pyrofosfat i närvaro av dubbelsträngat RNA. Dessa oligonukleotider aktiverar endoribonukleas (RNas L) som k lyver enkelsträngat RNA. Interferon kan inducera dessa reaktioner. EC 2.7.7.-.

Engelsk definition

An enzyme that catalyzes the conversion of ATP into a series of (2'-5') linked oligoadenylates and pyrophosphate in the presence of double-stranded RNA. These oligonucleotides activate an endoribonuclease (RNase L) which cleaves single-stranded RNA. Interferons can act as inducers of these reactions.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

2',5' Oligoadenylate Synthetase Synthetase, 2',5'-Oligoadenylate 2,5 Oligoadenylate Polymerase Oligoadenylate Polymerase, 2,5 Polymerase, 2,5 Oligoadenylate 2',5'-Oligoadenylate Polymerase 2',5' Oligoadenylate Polymerase Polymerase, 2',5'-Oligoadenylate (2'-5')An Polymerase ATP-(2'-5')oligo(A)adenylyltransferase 2',5'-Oligo(A) Synthetase 2',5'-Oligo(A) Polymerase 2,5 Oligoadenylate Synthetase Oligoadenylate Synthetase, 2,5 Synthetase, 2,5 Oligoadenylate 2-5A Synthetase