Svensk definition
Ett glykoprotein som migrerar som beta-globulin. Molekylvikten, 52 000 eller 95 000-115 000, antyder att den förekommer som dimer. Proteinet binder testosteron, dihydrotestosteron och östradiol i plasma. Könshormonbindande globulin har samma aminosyrasekvens som androgenbindande protein. De syntetiseras dock på olika platser och genomgår olika oligosackaridmodifikationer efter translation.
Engelsk definition
A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Sex hormone-binding protein has the same amino acid sequence as ANDROGEN-BINDING PROTEIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications.
Svenska synonymer
Sexualhormonbindande globulin — SHBG
Engelska synonymer
Globulin, Sex Hormone-Binding — Hormone-Binding Globulin, Sex — Sex Hormone Binding Globulin — Sex Steroid-Binding Protein — Sex Steroid Binding Protein — Steroid-Binding Protein, Sex — Testosterone-Estradiol Binding Globulin — Binding Globulin, Testosterone-Estradiol — Globulin, Testosterone-Estradiol Binding — Testosterone Estradiol Binding Globulin