Lactase-Phlorizin Hydrolase

Laktas-florizinhydrolas

Svensk definition

Ett enzym som hydrolyserar glykosyl-N-acylsfingosin till ett socker och N-acylsfingosin. Det katalyserar även hydrolys av florizin till floretin och glukos. Enzymet finns i tarmarnas borstbrämmembran, ofta ihop med laktas. EC 3.2.1.62.

Engelsk definition

A multifunctional protein that contains two enzyme domains. The first domain (EC 3.2.1.62) hydrolyzes glycosyl-N-acylsphingosine to a sugar and N-acylsphingosine. The second domain (EC 3.2.1.108) hydrolyzes LACTOSE and is found in the intestinal brush border membrane. Loss of activity for this enzyme in humans results in LACTOSE INTOLERANCE.

Svenska synonymer

Florizinhydrolas Laktas-glykosylceramidas

Engelska synonymer

Hydrolase, Lactase-Phlorizin Lactase Phlorizin Hydrolase Lactase-Glycosylceramidase Lactase Glycosylceramidase Phloretin-Glucosidase Phloretin Glucosidase Phlorizin Hydrolase Hydrolase, Phlorizin Glycosyl Ceramidase Ceramidase, Glycosyl Glycosylceramidase