En grupp autosomalt dominanta sjukdomar som kännetecknas av samtidig förekomst av cancer i två eller fler endokrina körtlar som utsöndrar peptidhormoner eller aminer. Dessa tumörer är ofta godartade, men kan vara elakartade. De klassificeras efter vilken körtel som är inbegripen och grad av aggressivitet. De två vanligaste formerna är MEN1 och MEN2, med genmutationer på kromosom 11 och 10.
A group of autosomal dominant diseases characterized by the combined occurrence of tumors involving two or more ENDOCRINE GLANDS that secrete PEPTIDE HORMONES or AMINES. These neoplasias are often benign but can be malignant. They are classified by the endocrine glands involved and the degree of aggressiveness. The two major forms are MEN1 and MEN2 with gene mutations on CHROMOSOME 11 and CHROMOSOME 10, respectively.
Multipel endokrin neoplasi
Adenomatosis, Familial Endocrine — Adenomatoses, Familial Endocrine — Endocrine Adenomatoses, Familial — Endocrine Adenomatosis, Familial — Familial Endocrine Adenomatoses — Multiple Endocrine Neoplasms — Endocrine Neoplasms, Multiple — Neoplasms, Multiple Endocrine — Multiple Endocrine Adenomatosis — Neoplasia, Multiple Endocrine — Adenomatosis, Multiple Endocrine — Adenomatoses, Multiple Endocrine — Endocrine Adenomatoses, Multiple — Endocrine Adenomatosis, Multiple — Multiple Endocrine Adenomatoses — Multiple Endocrine Neoplasia Syndromes — Multiple Endocrine Adenopathy — Adenopathies, Multiple Endocrine — Adenopathy, Multiple Endocrine — Endocrine Adenopathies, Multiple — Endocrine Adenopathy, Multiple — Multiple Endocrine Adenopathies — Familial Endocrine Adenomatosis — Multiple Endocrine Neoplasia Syndrome — Endocrine Neoplasia, Multiple