Ett enzym som utsöndras från levern till blodplasman hos många däggdjursarter. Det katalyserar förestringen av hydroxylgruppen i lipoproteinkolesterol genom överföring av en fettsyra från lecitinets C-2-position. Vid ärftlig lecitin:kolesterolacetyltransferasbrist leder brist på enzymet till ackumulering av icke-förestrat kolesterol i blodplasman. EC 2.3.1.43.
An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma.
Inga svenska synonymer finns.
O-Acyltransferase, Phosphatidylcholine-Sterol — Phosphatidylcholine Sterol O Acyltransferase — Lecithin Cholesterol Acyltransferase — Acyltransferase, Lecithin Cholesterol — Cholesterol Acyltransferase, Lecithin — Lecithin Acyltransferase — Acyltransferase, Lecithin — Cholesterol Ester Lysolecithin Acyltransferase — Phosophatidylcholine-Sterol Acyltransferase — Acyltransferase, Phosophatidylcholine-Sterol — Phosophatidylcholine Sterol Acyltransferase