Svensk definition
Deacetylaser som avlägsnar N-acetylgrupper från sidokedjorna till aminosyror i histoner. Några av dessa tillhör proteinfamiljen sirtuiner.
Histone Deacetylases
Histondeacetylaser
Engelsk definition
Deacetylases that remove N-acetyl groups from amino side chains of the amino acids of HISTONES. The enzyme family can be divided into at least three structurally-defined subclasses. Class I and class II deacetylases utilize a zinc-dependent mechanism. The sirtuin histone deacetylases belong to class III and are NAD-dependent enzymes.
Svenska synonymer
Inga svenska synonymer finns.
Engelska synonymer
Deacetylases, Histone — Histone Deacetylase — Deacetylase, Histone — HDAC Proteins — Histone Deacetylase Complexes — Complexes, Histone Deacetylase — Deacetylase Complexes, Histone — Class I Histone Deacetylases — Class II Histone Deacetylases