GTP Cyclohydrolase

GTP-cyklohydrolas

Svensk definition

GTP-cyklohydrolas I eller pyrofosfatbildande GTP 7,8-8,9-dihydrolas (GTP-cyklohydrolas II). En enzymgrupp som hydrolyserar imidazolringen i GTP, varvid kol-8 frigörs som format. Två C-N-bindningar hydrolyseras, och pentasenheten isomeriseras. Detta är första steget i syntesen av folsyra från GTP. EC 3.5.4.16 (GTP-cyklohydrolas I) och EC 3.5.4.25 (GTP-cyklohydrolas II).

Engelsk definition

(GTP cyclohydrolase I) or GTP 7,8-8,9-dihydrolase (pyrophosphate-forming) (GTP cyclohydrolase II). An enzyme group that hydrolyzes the imidazole ring of GTP, releasing carbon-8 as formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized. This is the first step in the synthesis of folic acid from GTP. EC 3.5.4.16 (GTP cyclohydrolase I) and EC 3.5.4.25 (GTP cyclohydrolase II).

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Cyclohydrolase, GTP GTP 8-Formylhydrolase 8-Formylhydrolase, GTP GTP 8 Formylhydrolase GTP Ring-Opening Enzyme GTP Ring Opening Enzyme Ring-Opening Enzyme, GTP GTP Dihydrolase Dihydrolase, GTP 7,8-Dihydroneopterintriphosphate Synthetase 7,8 Dihydroneopterintriphosphate Synthetase Synthetase, 7,8-Dihydroneopterintriphosphate GTP Cyclohydrolase II Cyclohydrolase II, GTP GTP Cyclohydrolase I Cyclohydrolase I, GTP