Fluorouracil

Fluorouracil

Svensk definition

En pyrimidinanalog som utgör en antimetabolit mot tumörer. Den stör DNA-syntesen genom att blockera den tymidylatsyntetasförmedlade omvandlingen av deoxiuridylsyra till tymidylsyra.

Engelsk definition

A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.

Svenska synonymer

5-FU Fluorouracilnatriumsalt

Engelska synonymer

5FU 5-FU 5-Fluorouracil 5 Fluorouracil Fluoruracil 5-FU Lederle 5 FU Lederle 5-FU Medac 5 FU Medac 5-HU Hexal 5 HU Hexal Adrucil Carac Efudix Fluoro-Uracile ICN Fluoro Uracile ICN Efudex Fluoroplex Flurodex Fluorouracil Mononitrate Fluorouracil Monopotassium Salt Fluorouracil Monosodium Salt Fluorouracil Potassium Salt Fluorouracil-GRY Fluorouracil GRY Fluorouracile Dakota Dakota, Fluorouracile Fluorouracilo Ferrer Far Fluracedyl Haemato-FU Haemato FU Neofluor Onkofluor Ribofluor 5-Fluorouracil-Biosyn 5 Fluorouracil Biosyn