Svensk definition
En pyrimidinanalog som utgör en antimetabolit mot tumörer. Den stör DNA-syntesen genom att blockera den tymidylatsyntetasförmedlade omvandlingen av deoxiuridylsyra till tymidylsyra.
Fluorouracil
Fluorouracil
Engelsk definition
A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
Svenska synonymer
5-FU — Fluorouracilnatriumsalt
Engelska synonymer
5-Fluorouracil — 5 Fluorouracil — Fluoruracil — 5-FU — 5FU — Efudix — Efudex — Fluoro-Uracile ICN — Fluoro Uracile ICN — Adrucil — Fluoroplex — Flurodex — Fluorouracil Monosodium Salt — Fluorouracil Potassium Salt — Fluorouracil Mononitrate — Fluorouracil Monopotassium Salt — Carac — 5-Fluorouracil-Biosyn — 5 Fluorouracil Biosyn — 5-HU Hexal — 5 HU Hexal — 5-FU Lederle — 5 FU Lederle — 5-FU Medac — 5 FU Medac — Fluorouracil-GRY — Fluorouracil GRY — Fluorouracilo Ferrer Far — Fluorouracile Dakota — Dakota, Fluorouracile — Haemato-FU — Haemato FU — Neofluor — Onkofluor — Ribofluor — Fluracedyl