Epilepsy, Tonic-Clonic

Tonisk-klonisk epilepsi

Svensk definition

En generaliserad epileptisk sjukdom som kännetecknas av återkommande, svårartade, motoriska anfall ("grand mal"). Den inledande toniska fasen kännetecknas av en böjning av bålen som åtföljs av sträckning av extremiteter och bål. Den klonisk fasen utmärks av rytmiska flexorryckningar i bål, armar och ben, pupillvidgning, blodtrycks- och pulsökning, urinavgång och bitande i tungan. Därpå försjunker den drabbade i medvetslöshet (det postiktala stadiet), som inom minuter till någon timme gradvis avtar. Epilepsin kan vara kryptogen, ärftlig eller symtomatisk (dvs en följd av annan, befintlig sjukdom eller skada).

Engelsk definition

A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)

Svenska synonymer

Grand mal-epilepsi Tonisk-kloniskt anfall Familjär tonisk-klonisk epilepsi

Engelska synonymer

Epilepsies, Tonic-Clonic Epilepsy, Tonic Clonic Tonic-Clonic Epilepsies Tonic-Clonic Epilepsy Convulsions, Grand Mal Convulsion, Grand Mal Grand Mal Convulsion Grand Mal Convulsions Epilepsy, Grand Mal Grand Mal Epilepsy Epilepsy, Major Major Epilepsies Major Epilepsy Grand Mal Seizure Disorder Major Motor Seizure Disorder Seizure Disorder, Grand Mal Seizure Disorder, Major Motor Seizure Disorder, Tonic Clonic Tonic Clonic Convulsions Convulsions, Tonic Clonic Convulsion, Tonic Clonic Tonic Clonic Convulsion Tonic-Clonic Convulsion Disorder Convulsion Disorders, Tonic-Clonic Convulsion Disorder, Tonic-Clonic Disorders, Tonic-Clonic Convulsion Disorder, Tonic-Clonic Convulsion Tonic Clonic Convulsion Disorder Tonic-Clonic Convulsion Disorders Tonic-Clonic Convulsion Syndrome Convulsion Syndromes, Tonic-Clonic Convulsion Syndrome, Tonic-Clonic Syndromes, Tonic-Clonic Convulsion Syndrome, Tonic-Clonic Convulsion Tonic Clonic Convulsion Syndrome Tonic-Clonic Convulsion Syndromes Tonic-Clonic Seizure Disorder Disorders, Tonic-Clonic Seizure Disorder, Tonic-Clonic Seizure Seizure Disorders, Tonic-Clonic Seizure Disorder, Tonic-Clonic Tonic Clonic Seizure Disorder Tonic-Clonic Seizure Disorders Tonic-Clonic Seizure Syndrome Seizure Syndromes, Tonic-Clonic Seizure Syndrome, Tonic-Clonic Syndromes, Tonic-Clonic Seizure Syndrome, Tonic-Clonic Seizure Tonic Clonic Seizure Syndrome Tonic-Clonic Seizure Syndromes Cryptogenic Tonic-Clonic Epilepsy Cryptogenic Tonic-Clonic Epilepsies Cryptogenic Tonic Clonic Epilepsy Epilepsies, Cryptogenic Tonic-Clonic Epilepsy, Cryptogenic Tonic-Clonic Tonic-Clonic Epilepsies, Cryptogenic Tonic-Clonic Epilepsy, Cryptogenic Epilepsy, Tonic-Clonic, Cryptogenic Epilepsy, Tonic-Clonic, Familial Familial Tonic-Clonic Epilepsy Epilepsies, Familial Tonic-Clonic Epilepsy, Familial Tonic-Clonic Familial Tonic-Clonic Epilepsies Familial Tonic Clonic Epilepsy Tonic-Clonic Epilepsies, Familial Tonic-Clonic Epilepsy, Familial Epilepsy, Tonic-Clonic, Symptomatic Symptomatic Tonic-Clonic Epilepsy Epilepsies, Symptomatic Tonic-Clonic Epilepsy, Symptomatic Tonic-Clonic Symptomatic Tonic-Clonic Epilepsies Symptomatic Tonic Clonic Epilepsy Tonic-Clonic Epilepsies, Symptomatic Tonic-Clonic Epilepsy, Symptomatic