DNA-topoisomeraser som katalyserar ATP-beroende klyvning av den ena av de två DNA-strängarna, genomföring av den obrutna strängen genom brottpunkten och återförening av den kluvna strängen. Typ 1-DNA-topoisomeraser minskar belastningen på DNA-strukturen genom att relaxera superhelixvindlingarna och knutringarna i DNA-spiralen. EC 5.99.1.2.
DNA TOPOISOMERASES that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. DNA Topoisomerases, Type I enzymes reduce the topological stress in the DNA structure by relaxing the superhelical turns and knotted rings in the DNA helix.
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DNA Relaxing Enzymes — DNA Relaxing Enzyme — DNA Relaxing Protein — DNA Topoisomerase — DNA Topoisomerase I — DNA Type 1 Topoisomerase — DNA Untwisting Enzymes — DNA Untwisting Enzyme — DNA Untwisting Proteins — DNA Untwisting Protein — Topoisomerase I — Type I DNA Topoisomerase — DNA Nicking-Closing Proteins — DNA Nicking-Closing Protein — DNA Topoisomerase III beta — Topoisomerase IIIbeta — IIIbeta, Topoisomerase — Topoisomerase III beta — III beta, Topoisomerase — beta, Topoisomerase III — DNA Topoisomerase III — III, DNA Topoisomerase — Topoisomerase III, DNA — TOP3 Topoisomerase — Topoisomerase, TOP3 — Topo III — III, Topo — Topoisomerase III — III, Topoisomerase — DNA Topoisomerase III alpha — TOPO IIIalpha — IIIalpha, TOPO — Topoisomerase IIIalpha — IIIalpha, Topoisomerase — TOP3alpha