Dianhydrogalactitol

Dianhydrogalaktitol

Svensk definition

En av de cytotoxiska dihalohexitoler som kan ha alkylerande antitumörverkan. Ämnet orsakar benmärgsförgiftning. Den aktiva formen tros vara diepoxiden.

Engelsk definition

One of the cytotoxic dihalohexitols that alkylates and cross-links DNA via an epoxide group during all phases of the cell cycle, resulting in a disruption of DNA function and cell cycle arrest. It has antineoplastic activity and also causes bone marrow toxicity.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Dianhydrodulcitol Diepoxydulcitol Diepoxygalactitol 1,2,5,6-Dianhydrogalactitol 1,2-5,6-Dianhydrogalactitol NSC-132313 NSC132313 NSC 132313