Engelsk definition
An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
Svenska synonymer
Platinol
Engelska synonymer
cis-Diamminedichloroplatinum(II) — Platinum Diamminodichloride — Diamminodichloride, Platinum — cis-Platinum — cis Platinum — Dichlorodiammineplatinum — cis-Diamminedichloroplatinum — cis Diamminedichloroplatinum — cis-Dichlorodiammineplatinum(II) — NSC-119875 — Platino — Platinol — Biocisplatinum — Platidiam