Ett enzym i transferasklassen som katalyserar kondensationen av succinylgruppen från succinylkoenzym A med glycin vid bildandet av delta-aminlevulinat. Det är ett pyridoxylfosfatprotein, och reaktione n äger rum i mitokondrierna som det första steget i hembiosyntesen. Enzymet har en nyckelroll i reglerandet av hembiosyntesen och, åtminstone i levern, "feedback"-hämmas av hem.
An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37.
Inga svenska synonymer finns.
5 Aminolevulinate Synthetase — Synthetase, 5-Aminolevulinate — delta-Aminolevulinate Synthase — Synthase, delta-Aminolevulinate — delta Aminolevulinate Synthase — 5-Aminolevulinate Synthase — 5 Aminolevulinate Synthase — Synthase, 5-Aminolevulinate — Aminolevulinic Acid Synthetase — Acid Synthetase, Aminolevulinic — Synthetase, Aminolevulinic Acid — delta-Aminolevulinic Acid Synthetase — Acid Synthetase, delta-Aminolevulinic — Synthetase, delta-Aminolevulinic Acid — delta Aminolevulinic Acid Synthetase