Expansion of blood cells arising from mutant HEMATOPOIETIC STEM CELLS often related to aging. Mutations on epigenetic regulator genes are common in clonal hematopoiesis and may be a risk factor for HEMATOLOGIC NEOPLASMS and other cardiovascular diseases. When variant allele fraction is at least 2% and is present in the absence of severe cytopenias it is referred to as clonal hematopoiesis of indeterminate potential (CHIP).
Åldersrelaterad klonal hematopoes
Hematopoiesis, Clonal — Clonal Cytopenia of Undetermined Significance — CCUS Clonal Cytopenia of Undetermined Significance — CHIP Clonal Hematopoiesis of Indeterminate Potential — Clonal Hematopoiesis of Indeterminate Potential — Idiopathic Cytopenias of Undetermined Significance — ICUS Idiopathic Cytopenias of Undetermined Significance — Age-related Clonal Hematopoiesis — Age related Clonal Hematopoiesis — Clonal Hematopoiesis, Age-related — Hematopoiesis, Age-related Clonal — ARCH Age-related Clonal Hematopoiesis — ARCH Age related Clonal Hematopoiesis