Deubiquitinating Enzyme CYLD

Engelsk definition

A deubiquitinase and tumor-suppressor protein that specifically cleaves LYSINE-63-linked polyubiquitin chains and also has endodeubiquitinase activity. It functions to regulate NF-KAPPA B and WNT SIGNALING PATHWAY activity, contributing to cell survival, proliferation, and differentiation. Mutations in the CYLD gene are associated with cases of FAMILIAL CYLINDROMATOSIS.

Svenska synonymer

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Engelska synonymer

CYLD, Deubiquitinating Enzyme Cylindromatosis Protein Deubiquitinating Enzyme Cylindromatosis Cylindromatosis, Deubiquitinating Enzyme CYLD Protein