Svensk definition
Oral HCV-proteasehämmare som är effektiv mot hepatit C-virus (HCV) serinprotease NS3/4A. Den används vid behandling av kronisk hepatit C (antiviral) genotyp-1-infektion hos vuxna med kompenserad leversjukdom, inklusive skrumplever.
Simeprevir
Simeprevir
Engelsk definition
Oral HCV-PROTEASE INHIBITOR effective against hepatitis C virus (HCV) serine protease NS3/4A. It is used in the treatment of chronic hepatitis C (Antivirals) genotype 1 infection in adults with compensated liver disease, including CIRRHOSIS.
Svenska synonymer
Olysio
Engelska synonymer
N-(17-(2-(4-isopropylthiazole-2-yl)-7-methoxy-8-methylquinolin-4-yloxy)-13-methyl-2,14-dioxo-3,13-diazatricyclo(13.3.0.04,6)octadec-7-ene-4-carbonyl)(cyclopropyl)sulfonamide — TMC 435350 — 435350, TMC — TMC435350 — TMC-435350 — TMC 435 — 435, TMC — TMC435 — TMC-435 — Olysio