A transcription factor that dimerizes with the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. It contains a highly conserved DNA-binding domain known as the runt domain. Runx1 is frequently mutated in human LEUKEMIAS.
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Runx1 Protein — Pebp2a2 Protein — Runt-Related Transcription Factor 1 — Runt Related Transcription Factor 1 — Acute Myeloid Leukemia 1 Protein — Core-Binding Factor Alpha 2 Protein — Core Binding Factor Alpha 2 Protein — Acute Myeloid Leukemia 1D Protein — AML1D Protein — Acute Myeloid Leukemia 1C Protein — AML1C Protein — Acute Myeloid Leukemia 1B Protein — AML1B Protein — Acute Myeloid Leukemia 1A Protein — AML1A Protein