Complement Pathway, Mannose-Binding Lectin

Komplementaktivering, mannosbindande lektin

Svensk definition

Komplementaktivering utlöst av samverkan mellan mikrobiella polysackarider och mannosbindande lektin i serum, vilket leder till aktivering av mannosbindande proteinassocierade serinproteaser (MASP). Precis som vid det klassiska förloppet klyver MASPar komplement C4 och C2 till C3-konvertas (C4B2A) och därpå följande C5-konvertas (C4B2A3B), vilket ger spjälkning av komplement C5 och sammanfogning av membranattackkomplex.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Complement Pathway, Mannose Binding Lectin Lectin-Complement Pathway Lectin Complement Pathway Lectin-Complement Pathways Pathway, Lectin-Complement Pathways, Lectin-Complement Mannan-Binding Lectin Complement Pathway Mannan Binding Lectin Complement Pathway Mannose-Binding Lectin Complement Pathway Mannose Binding Lectin Complement Pathway Mannan-Binding Lectin Pathway (Complement Activation) Lectin Pathway, Mannan-Binding (Complement Activation) Lectin Pathways, Mannan-Binding (Complement Activation) Mannan Binding Lectin Pathway (Complement Activation) Mannan-Binding Lectin Pathways (Complement Activation) Pathway, Mannan-Binding Lectin (Complement Activation) Pathways, Mannan-Binding Lectin (Complement Activation)