RNA-bindande protein FUS

Engelsk definition

A multifunctional heterogeneous-nuclear ribonucleoprotein that may play a role in homologous DNA pairing and recombination. The N-terminal portion of protein is a potent transcriptional activator, while the C terminus is required for RNA binding. The name FUS refers to the fact that genetic recombination events result in fusion oncogene proteins (ONCOGENE PROTEINS, FUSION) that contain the N-terminal region of this protein. These fusion proteins have been found in myxoid liposarcoma (LIPOSARCOMA, MYXOID) and acute myeloid leukemia.

Svenska synonymer

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Engelska synonymer

RNA Binding Protein FUS — TLS Protein — hnRNP P2 — POMp75 Protein — Translocated in Liposarcoma Protein — FUS RNA-Binding Protein — FUS RNA Binding Protein — RNA-Binding Protein, FUS — Fusion Protein in Myxoid Liposarcoma — FUS Protein

RNA-Binding Protein FUS