Oncogene Protein gp140(v-fms)

Onkogenprotein gp140(v-fms)

Engelsk definition

Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus (SM-FeSV). The oncogene protein v-fms lacks sequences, which, in the highly homologous proto-oncogene protein c-fms (CSF-1 receptor), normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120(v-fms) is post-translationally modified to generate gp140(v-fms).

Svenska synonymer

v-fms protein — gp 120 v-fms — fms onkogenprodukt gp120 — fms onkogenprotein gp120

Engelska synonymer

v-fms Protein — v fms Protein — gp140 v-fms — gp140 v fms — v-fms, gp140 — gp140(v-fms) — fms Oncogene Product gp140 — fms Oncogene Protein gp140 — fms Oncogene Protein gp120 — gp120(v-fms) — gp120 v-fms — gp120 v fms — v-fms, gp120 — fms Oncogene Product gp120