Arylsulfotransferase

Arylsulfotransferas

Svensk definition

Ett sulfotransferas som katalyserar sulfateringen av fenol i närvaro av 3´-fosfoadenylylsulfat som sulfatgivare till ett arylsulfat och adenosin-3´,5´-bifosfat. Ett antal aromatiska föreningar kan fun gera som mottagare; organiska hydroxylaminer kan dock icke vara substrat. Sulfatkonjugering med detta enzym är en väsentlig process i biotransformeringen av fenol- och katekolläkemedel samt neurotrans mittorer. EC 2.8.2.1.

Engelsk definition

A sulfotransferase that catalyzes the sulfation of a phenol in the presence of 3'-phosphoadenylylsulfate as sulfate donor to yield an aryl sulfate and adenosine 3',5'-bisphosphate. A number of aromatic compounds can act as acceptors; however, organic hydroxylamines are not substrates. Sulfate conjugation by this enzyme is a major pathway for the biotransformation of phenolic and catechol drugs as well as neurotransmitters. EC 2.8.2.1.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Aryl Sulfotransferase Sulfotransferase, Aryl Phenolsulfokinase Phenol Sulfotransferase Sulfotransferase, Phenol Sulfokinase Phenol Sulfokinase Flavonoid Sulfotransferase Sulfotransferase, Flavonoid Phenol Sulfotransferase M Sulfotransferase M, Phenol Catecholamine Sulfotransferase B Sulfotransferase B, Catecholamine Acetaminophen Sulphotransferase Sulphotransferase, Acetaminophen Catecholamine Sulfotransferase A Sulfotransferase A, Catecholamine Dopamine Sulfotransferase Sulfotransferase, Dopamine Phenolsulfotransferase P Phenol Sulfotransferase P Sulfotransferase P, Phenol