Svensk definition
Ett sulfotransferas som katalyserar sulfateringen av fenol i närvaro av 3´-fosfoadenylylsulfat som sulfatgivare till ett arylsulfat och adenosin-3´,5´-bifosfat. Ett antal aromatiska föreningar kan fun gera som mottagare; organiska hydroxylaminer kan dock icke vara substrat. Sulfatkonjugering med detta enzym är en väsentlig process i biotransformeringen av fenol- och katekolläkemedel samt neurotrans mittorer. EC 2.8.2.1.
Engelsk definition
A sulfotransferase that catalyzes the sulfation of a phenol in the presence of 3'-phosphoadenylylsulfate as sulfate donor to yield an aryl sulfate and adenosine 3',5'-bisphosphate. A number of aromatic compounds can act as acceptors; however, organic hydroxylamines are not substrates. Sulfate conjugation by this enzyme is a major pathway for the biotransformation of phenolic and catechol drugs as well as neurotransmitters. EC 2.8.2.1.
Svenska synonymer
Inga svenska synonymer finns.
Engelska synonymer
Aryl Sulfotransferase — Sulfotransferase, Aryl — Phenolsulfokinase — Phenol Sulfotransferase — Sulfotransferase, Phenol — Sulfokinase — Phenol Sulfokinase — Flavonoid Sulfotransferase — Sulfotransferase, Flavonoid — Phenol Sulfotransferase M — Sulfotransferase M, Phenol — Catecholamine Sulfotransferase B — Sulfotransferase B, Catecholamine — Acetaminophen Sulphotransferase — Sulphotransferase, Acetaminophen — Catecholamine Sulfotransferase A — Sulfotransferase A, Catecholamine — Dopamine Sulfotransferase — Sulfotransferase, Dopamine — Phenolsulfotransferase P — Phenol Sulfotransferase P — Sulfotransferase P, Phenol