Glutamate Decarboxylase

Glutamatdekarboxylas

Svensk definition

Ett pyridoxal-fosfatprotein som katalyserar alfadekarboxilering av L-glutaminsyra till att ge gammaaminosmörsyra och koldioxid. Enzymet finns i bakterier och i nervsystemet hos såväl ryggradsdjur som ryggradslösa. Enzymet reglerar halterna av gammaaminosmörsyra i normal nervvävnad. Hjärnenzymet verkar även på L-cysteat, L-cysteinsulfinat och L-aspartat. EC 4.1.1.15.

Engelsk definition

A pyridoxal-phosphate protein that catalyzes the alpha-decarboxylation of L-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. The enzyme is found in bacteria and in invertebrate and vertebrate nervous systems. It is the rate-limiting enzyme in determining GAMMA-AMINOBUTYRIC ACID levels in normal nervous tissues. The brain enzyme also acts on L-cysteate, L-cysteine sulfinate, and L-aspartate. EC 4.1.1.15.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Decarboxylase, Glutamate Glutamic Acid Decarboxylase Acid Decarboxylase, Glutamic Decarboxylase, Glutamic Acid Glutamate Carboxy-Lyase Carboxy-Lyase, Glutamate Glutamate Carboxy Lyase