Svensk definition
En transkriptionsregulator hos prokaryoter som verkar vid flera promotorer, sedan den aktiverats genom bindning till cykliskt AMP (cAMP). Detta receptorprotein identifierades ursprungligen som ett katabolismgenaktiveringsprotein. Det har senare visat sig reglera flera funktioner ej förknippade med katabolism, samt att fungera som såväl negativ som positiv transkriptionsregulator. Hit räknas inte cellytereceptorer för cyklist AMP (cykliskt AMP-receptorer) eller eukaryota cytoplasmatiska cAMP-receptorproteiner, vilka utgör regulatorenheterna hos cAMP-beroende proteinkinaser.
Engelsk definition
A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (CYCLIC AMP RECEPTORS), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES.
Svenska synonymer
Inga svenska synonymer finns.
Engelska synonymer
cAMP Receptor Proteins — Proteins, cAMP Receptor — Receptor Proteins, cAMP — Catabolic Gene Activator — Gene Activator, Catabolic — Gene Activators, Catabolic — Catabolic Gene Activators — Cyclic AMP Receptor Proteins — Activator Protein, Catabolite — Activator Proteins, Catabolite — Catabolite Activator Proteins — Protein, Catabolite Activator — Proteins, Catabolite Activator — Catabolite Activator Protein — Catabolite Gene Activator Protein — Catabolite Gene Activator Proteins — Catabolite Regulator Protein — Catabolite Regulator Proteins — Protein, Catabolite Regulator — Proteins, Catabolite Regulator — Regulator Protein, Catabolite — Regulator Proteins, Catabolite — cAMP Receptor Protein — Protein, cAMP Receptor — Receptor Protein, cAMP — Activator, Catabolic Gene — Activators, Catabolic Gene