Elongin

Elongin

Engelsk definition

A heterotrimeric protein complex composed of 110 kDa elongin A, 18 kDa elongin B, and 15 kDa elongin C subunits. It functions as a positive regulator of RNA POLYMERASE II, increasing its rate of transcriptional elongation by suppressing transient pausing along the DNA template. Elongin A is the transcriptionally active component; elongins B and C enhance its activity.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Elongin Complex — Complex, Elongin — SIII Elongation Factor — Elongation Factor, SIII — Transcription Factor SIII — SIII, Transcription Factor — TF-SIII — Elongin A — EloA Protein — Elongin B — EloB Protein — Elongin C — EloC Protein