Autophagy-Related Protein 5

Autofagi-relaterat protein 5

Engelsk definition

An autophagy-related protein that functions in AUTOPHAGOSOME biogenesis. It is conjugated to the ATG12 PROTEIN via a process that is similar to UBIQUITINATION and involves the ATG7 PROTEIN and ATG10 enzyme. The ATG12-ATG5 conjugate acts as an E3 UBIQUITIN LIGASE-like enzyme and is required for the localization of ATG8 PROTEINS to AUTOPHAGOSOME vesicle membranes and modification of membrane lipids.

Svenska synonymer

ATG5 protein

Engelska synonymer

Autophagy Related Protein 5 — Apoptosis-Specific Protein — Apoptosis Specific Protein — ATG5 Protein — ATG-5 Protein — ATG 5 Protein — Autophagy Protein-5 — Autophagy Protein 5 — Autophagy-Related 5 Protein — Autophagy Related 5 Protein