Hexamethonium

Hexametonium

Svensk definition

En kolinerg nikotinreceptorantagonist som ibland kallas ganglieblockerarprototypen. Den tas med svårighet upp i mag-tarmkanalen och passerar inte blod-hjärnbarriären. Ämnet har använts för en rad terapeutiska ändamål, bl a behandling av högt blodtryck, men har, liksom andra ganglieblockerare, ersatts av mer specifika läkemedel. Inom forskningen har det dock utbredd användning.

Engelsk definition

A nicotinic cholinergic antagonist often referred to as the prototypical ganglionic blocker. It is poorly absorbed from the gastrointestinal tract and does not cross the blood-brain barrier. It has been used for a variety of therapeutic purposes including hypertension but, like the other ganglionic blockers, it has been replaced by more specific drugs for most purposes, although it is widely used a research tool.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

Hexonium Hexamethonium Dihydroxide Dihydroxide, Hexamethonium Hexamethonium Diiodide Diiodide, Hexamethonium Hexamethonium Dimethylsulfate Dimethylsulfate, Hexamethonium Hexamethonium Diperchlorate Diperchlorate, Hexamethonium Hexamethonium Iodide Iodide, Hexamethonium Hexamethonium Dibromide Dihydrate Dibromide Dihydrate, Hexamethonium Dihydrate, Hexamethonium Dibromide Depressin Hexamethonium Bitartrate Bitartrate, Hexamethonium Hexamethonium Bromide Bromide, Hexamethonium Hexamethonium Chloride Chloride, Hexamethonium Hexamethonium Dibromide Dibromide, Hexamethonium Hexamethonium Dichloride Dihydrate Dichloride Dihydrate, Hexamethonium Dihydrate, Hexamethonium Dichloride Hexamethonium Monotartrate Monotartrate, Hexamethonium