Phorbol 12,13-Dibutyrate

Forbol 12,13-dibutyrat

Svensk definition

En forbolester som finns i krotonolja. Förutom att framkalla hudtumörer aktiverar ämnet effektivt kalciumutlöst, fosfolipidberoende proteinkinas (proteinkinas C). Tack vare denna egenskap har forbol 12,13-dibutyrat genomgripande verkan på många biologiska system.

Engelsk definition

A phorbol ester found in CROTON OIL which, in addition to being a potent skin tumor promoter, is also an effective activator of calcium-activated, phospholipid-dependent protein kinase (protein kinase C). Due to its activation of this enzyme, phorbol 12,13-dibutyrate profoundly affects many different biological systems.

Svenska synonymer

Inga svenska synonymer finns.

Engelska synonymer

12,13-Dibutyrate, Phorbol Phorbol-12,13-Dibutyrate Phorbol 12,13 Dibutyrate