Svensk definition
Ett medel mot fett som sänker halterna av kolesterol, triglycerider, serum-betalipoproteiner och fosfolipider. Det verkar genom att störa de enzymatiska stegen i omvandlingen av acetat till hydroximetylglutaryl-CoA samt genom att blockera effekten av hydroximetylglutaryl-CoA-reduktas, som är det produktionshämmande enzymet i kolesterolbiosyntesen.
Engelsk definition
An antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethylglutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate limiting enzyme in the biosynthesis of cholesterol.
Svenska synonymer
Inga svenska synonymer finns.
Engelska synonymer
3-Hydroxy-3-methylpentanedioic Acid — 3 Hydroxy 3 methylpentanedioic Acid — Acid, 3-Hydroxy-3-methylpentanedioic — beta-Hydroxy-beta-Methylglutarate — beta Hydroxy beta Methylglutarate — 3-Hydroxy-3-methylglutaric Acid — 3 Hydroxy 3 methylglutaric Acid — Acid, 3-Hydroxy-3-methylglutaric