Svensk definition
Antikroppsförmedlad destruktion av målceller genom icke-sensibiliserade effektorceller. Målcellens identitet kan variera, men den måste ha yt-IgG med intakt Fc-del. Effektorcellen är en mördarcell med FC-receptorer, och den kan utgöras av en lymfocyt i avsaknad av vanliga B- eller T-cellmarkörer, en monocyt, makrofag eller polynukleär leukocyt. Reaktionen är komplementberoende.
Engelsk definition
The phenomenon of antibody-mediated target cell destruction by non-sensitized effector cells. The identity of the target cell varies, but it must possess surface IMMUNOGLOBULIN G whose Fc portion is intact. The effector cell is a "killer" cell possessing Fc receptors. It may be a lymphocyte lacking conventional B- or T-cell markers, or a monocyte, macrophage, or polynuclear leukocyte, depending on the identity of the target cell. The reaction is complement-independent.
Svenska synonymer
Antikroppsberoende cytotoxicitet
Engelska synonymer
Antibody Dependent Cell Cytotoxicity — Cell Cytoxicity, Antibody-Dependent — Antibody-Dependent Cell Cytoxicities — Antibody-Dependent Cell Cytoxicity — Cell Cytoxicities, Antibody-Dependent — Cell Cytoxicity, Antibody Dependent — Cytoxicities, Antibody-Dependent Cell — Cytoxicity, Antibody-Dependent Cell — ADCC — Cytotoxicity, Antibody-Dependent Cell — Antibody-Dependent Cell Cytotoxicities — Cell Cytotoxicities, Antibody-Dependent — Cell Cytotoxicity, Antibody-Dependent — Cytotoxicities, Antibody-Dependent Cell — Cytotoxicity, Antibody Dependent Cell