A component of CRISPR-Cas SYSTEMS. Cas endodeoxyribonucleases assemble with a guide RNA complex, a hybrid of CRISPR RNA (crRNA) and transactivating crRNA (tracrRNA) molecules, to form an active complex that cleaves DNA. crRNA and tracrRNA can be synthetically fused into a single RNA molecule, namely single guide RNA. Synthetic sgRNA is used with CRISPR-Cas SYSTEMS for targeted GENE EDITING.
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RNA, Guide (CRISPR-Cas Systems) — Guide RNA, CRISPR-Cas Systems — Guide RNA, CRISPR Cas Systems — Guide RNA (CRISPR-Cas Systems) — RNA, CRISPR Guide — Guide RNA, CRISPR — crRNA — CRISPR Guide RNA — RNA, Single Guide — Guide RNA, Single — sgRNA (Single-Guide RNA) — CRISPR-Cas Systems sgRNA (Single Guide RNA) — sgRNA (CRISPR-Cas Systems) — RNA, Single-Guide — Single Guide RNA — Single-Guide RNA — crRNA, Transactivating — Transactivating crRNA — tracrRNA